Searchable abstracts of presentations at key conferences in endocrinology

ea0015p126 | Diabetes, metabolism and cardiovascular | SFEBES2008

Identification of a circadian clock within adipocyte cells

Otway Daniella , Frost Gary , Johnston Jonathan

Multiple aspects of physiology and pathophysiology, including endocrine function, are influenced by endogenous circadian timing mechanisms. In mammals, cell autonomous clocks are present in all major tissues throughout the body. These clocks are synchronised via complex signalling pathways and are believed to drive local aspects of physiology.Recently published data have revealed 24-h rhythms in up to 20% of the adipose transcriptome, suggesting profound...